Up-to-date Information on
Waldenström’s macroglobulinemia



The state-of-the-art glossary for Waldenström’s macroglobulinemia.


Cyclophosphamide in the glossary for Waldenström's macroglobulinemia

An immunosuppressive alkylating agent (chemotherapy).

Cyclophosphamide (also known as cytophosphane) used as a chemotherapeutic and immunosuppressive agent. As chemotherapy, it is used to treat a range of cancers, including lymphoma, multiple myeloma, leukemia, breast cancer and small cell lung cancer. As an immunosuppressive, it is used in the treatment of nephrotic syndrome, granulomatosis with polyangiitis, and following organ transplant. It is administered orally or intravenously. Cyclophosphamide is in the alkylating agent and nitrogen mustard family of medications and exerts its effect by interfering with the synthesis of RNA and the duplication of DNA. Cyclophosphamide was approved for medical use in the United States (US) in 1959, and is on the World Health Organization (WHO) List of Essential Medicines. Cyclophosphamide is authorized for use in the EU (cyclophosphamide SmPC).

Glossary overview