Glossary
The state-of-the-art glossary for Waldenström’s macroglobulinemia.
MYD88
MYD88 in the glossary for Waldenström's macroglobulinemia
MYD88 (myeloid differentiation factor 88) is a driver gene found in hematologic B-cell malignancies.
The MYD88 (myeloid differentiation factor 88) gene encodes a protein involved in signaling within immune cells. The MYD88 protein serves to transmit extracellular signals to within cells. MYD88 mutations are a driver in hematologic B-cell malignancies. The missense mutation (L265P) is found in ∼90% of Waldenström’s macroglobulinemia cases.
Glossary overview